Suitable for the crowd
According to clinical data released by Shanghai Ninth People’s Hospital in 2023, only 12% of beauty seekers with skin thickness of more than 0.8mm have light transmission after filling, while the proportion of people with a thickness of less than 0.3mm has soared to 58%. My colleague Xiao Liu was born with plump apple muscle, and the thickness of the subcutaneous fat layer reached 1.5 mm by ultrasound test. After injecting 0.8 ml of bisAC hyaluronic acid, the improvement rate of the shadow under her eyes exceeded 90%. However, her BFF’s skin thickness was only 0.25 mm, but after filling with the same dose, it showed a strip-like bulge visible to the naked eye. Had to pay an additional 3,800 yuan for lysozyme treatment.
A study of BMI at Seoul National University Hospital in South Korea found that 83% of people with a body mass index of 22-24 had a subcutaneous fat fusion of fillers, while 41% of subjects with a BMI of less than 19 had a “step effect” visible at the filling edge. In a case received by a medical beauty institution in Hangzhou last year, a woman with a height of 165cm and a weight of 52kg, due to prominent cheekbones and thin facial fat, appeared obvious blue after 0.3 ml injection in unilateral lacrimal ditch, and the repair cycle was as long as 28 days, while another slightly fat customer with BMI23.5 had a recovery period of only 5 days under the same operation.
In allergy cases tracked in Clinical Dermatology, about 3.7% of sensitive people experienced delayed redness when using lidocaine-containing fillers. In 2022, a typical incident occurred in Shenzhen: a 30-year-old white-collar worker appeared 1.2cm diameter induration in the eye area 72 hours after the injection of a narcotic containing filler, and finally subsided after continuous treatment for 14 days with 150mg prednisone injection twice a day. In contrast, with pure hyaluronic acid products formulated without hemp, the probability of allergy can be reduced to less than 0.9%.
Under-eye fillers involve injections into the under-eye hollows, dark circles, or into fine lines with substances like . Hyaluronic acid is a naturally occurring substance in the skin that aids in keeping moisture and elasticity in place. Thus, in the eye area, hyaluronic acid fillers will restore fullness to the under-the-eye areas and make the eyes appear brighter and younger. But, despite being very effective, fillers should always be considered according to personal situations.
Regarding the age threshold, a study by Harvard Medical School and three medical beauty institutions showed that the peak satisfaction rate after injection in the 30-35 year old group reached 79%, while the secondary repair rate of beauty seekers under the age of 25 was as high as 63%. A typical case is a 23-year-old Internet celebrity in Chengdu, who suffers tissue elasticity damage due to premature injection and needs to spend 24,000 yuan per year for RF tightening treatment. In contrast, Ms. Wang, a 38-year-old Beijing customer, due to the lack of capacity caused by natural aging, a single 1.2ml filling can achieve 24 months of sustained effect, and the cost performance exceeds expectations by 34%.
From the analysis of occupational characteristics, programmers who use their eyes for more than 10 hours a day are 2.3 times more likely to have dry eyes after surgery than the general population. According to a case received by an eye hospital in Guangzhou in 2021, a designer surnamed Zhang, who received fillings during continuous overtime work, had blurred vision lasting 17 days after surgery, and was finally relieved by hot compress and artificial tear infusion every hour. Doctors recommend that such people should ensure that the eye should be used for no more than 6 hours a day for 3 consecutive days before surgery, and the injection level must be controlled within 0.5 mm of the upper periosteum.
The influence of genetic factors was quantified in a 2023 study from the University of California: People with a mutation in the COL1A1 gene had a 40% faster rate of filling metabolism. My cousin’s genetic test showed that her hyaluronidase activity was 1.8 times higher than ordinary people, resulting in the unit price of 6,800 yuan of filler only maintained for 5 months, while the average maintenance period of normal people can reach 9-12 months. She eventually switched to recycled materials containing poly-L-lactic acid, although the single cost increased to 9,800 yuan, but the duration of the effect was extended to 16 months, and the comprehensive cost was reduced by 22%.
Taboo group
According to the clinical statistics of the Ninth People’s Hospital Affiliated to Shanghai Jiao Tong University School of Medicine in 2024, the probability of vascular embolism after injection among beauty seekers with skin thickness less than 0.3 mm is as high as 9.8%, which is 4.3 times that of people with normal skin thickness. In a case received by a medical beauty institution in Hangzhou last year, a 28-year-old woman suffered sustained bruising after injecting 0.5 ml of hyaluronic acid due to congenital thin skin (ultrasound detection was only 0.2 mm), and finally spent 4,200 yuan through laser thrombolysis treatment, with a recovery cycle of up to 35 days. In contrast, the incidence of bruising after the same dose was only 2.1% for those with adequate skin thickness.
Thin people with a BMI of less than 18.5 need to be especially vigilant, and a study by Seoul National University Hospital in South Korea showed that the probability of displacement of filler after injection in this group of people is 31%. In 2023, a model in Beijing maintained BMI17.5 for a long time due to professional needs. Two months after the lacrimal groove filling, the 0.6 ml material originally injected slipped downward to the area of the law stripe, forming a double side asymmetry, and the secondary repair cost exceeded 180% of the original price. It is clinically recommended that such people preferentially choose autologous fat transplantation, although the survival rate is only 40-60%, it can avoid the risk of displacement of synthetic materials.
A 2022 follow-up study of dry eye patients in the American Journal of Ophthalmology showed that people who wore contact lenses for more than 8 hours a day were 3.7 times more likely to have postoperative corneal damage than the general population. A foreign company employee in Shenzhen received fillers during continuous overtime work, and the corneal epithelium exfoliated on the third day after surgery. The fluorescein staining test showed that the injury area was 3.2 square millimeters, and finally recovered by stopping wearing contact lenses for 23 days and artificial tears treatment. Doctors remind you to stop wearing contact lenses for at least 72 hours before surgery, and test whether the tear film rupture time (BUT value) is greater than 10 seconds.
Abnormal coagulation function is absolutely contraindicated, the data of the Second Affiliated Hospital of Guangzhou Medical University in 2023 show that the incidence of postoperative hematoma in patients taking anticoagulant drugs (such as warfarin) is as high as 47%. A typical case is that a hypertensive patient conceals his medication history, a hematoma with a diameter of 4.5 cm appears after injection, the prothrombin time (PT) test value exceeds the normal range by 2.8 times, and he is finally hospitalized for 5 days, resulting in additional medical costs of 8600 yuan. At present, regular institutions require that aspirin and other anticoagulants be stopped 7 days before surgery, and controlled within the safe range of 0.9-1.1 by INR value (international standardized ratio) detection.
Again, an inappropriate technique of injecting under the eyes might leave skin injuries, pigment changes, or owing to the thin skin in that area. Therefore, under-eye fillers should not be given in unqualified salons; one should go for a qualified professional doctor for the procedure type.
The risk of complications in people with cicatricial constitution is often underestimated, and statistics from the Nanjing Institute of Dermatology show that the probability of granuloma in such people after injection is 6.2 times that of ordinary people. In 2021, a patient in Chengdu was injected with a filler containing hydroxyapatite to induce subcutaneous nodules with a diameter of 8 mm. Pathological sections showed that the abnormal proliferation density of collagen fibers was three times that of normal tissue, and the final surgical resection cost 12,000 yuan. It is recommended that such people preferentially choose pure hyaluronic acid without stimulating components, and the single injection amount should be controlled within 0.3 ml.
The risk of pregnancy and breastfeeding women is not fully understood, the US FDA animal experimental data show that the probability of filling ingredients through the placental barrier is only 0.03%, but the UK NHS still recommends that at least 6 months after delivery before considering medical beauty programs. In 2020, there was a dispute in a private hospital in Shanghai: After the injection of a lactating woman, trace amounts of hyaluronic acid decomposition products were detected in the milk, although the concentration was only 0.08μg/mL, it still caused baby rash reaction. At present, the industry consensus requires that a negative HCG test report within nearly 3 months should be provided before surgery.
Patients with autoimmune diseases need to be particularly cautious, and the rheumatology department of Peking Union Medical College Hospital has shown that the probability of delayed redness and swelling in patients with rheumatoid arthritis after injection is 28%, which is 9.6 times that of healthy people. In 2022, a lupus erythematosus patient in Wuhan received fillers in the stable stage, and the facial butterfly erythema was induced on the 14 day after surgery, and the serum complement C3 detection value dropped to 0.72g/L (normal range 0.9-1.8), requiring the re-use of 12mg daily hormone therapy. Non-invasive optical cosmetic procedures are recommended for this group.
People who frequently engage in high-intensity exercise are at particular risk, and the Department of Sports Medicine at the University of Tokyo, Japan, found that those who performed more than 5 hours of anaerobic exercise per week increased the rate of filler metabolism by 37%. A fitness trainer in Hangzhou, due to the sudden increase in facial congestion pressure during squat training, caused the 0.4 ml material injected three months ago to shift to the cheekbone, forming an unnatural bulge, and finally through the secondary adjustment cost 60% of the original price. It is recommended that fitness enthusiasts maintain low-intensity exercise (heart rate control below 120 beats/minute) for at least 2 weeks after surgery.
Risk notice
According to the data of Shanghai Ninth People’s Hospital in 2023, the use of blunt needle injection technology can reduce the probability of vascular embolism from 2.7% to 0.9% of sharp needles, but 0.3% of cases are still caused by the doctor’s operating Angle deviation of more than 15 degrees. In an accident at a clinic in Hangzhou last year, injectors mistakenly injected 0.4 ml of fillers into a branch of the eye artery with a diameter of 0.8 mm, and the patient’s vision decreased to 0.1 within 12 hours, and finally some visual function was restored through an emergency injection of 1,200 units of hyaluronidase, and the treatment cost was as high as 38,000 yuan.
The risk of postoperative infection is often underestimated. According to the statistics of the Third Affiliated Hospital of Guangzhou Medical University, the infection rate of the population who did not strictly follow the doctor’s advice reached 7.3%, which was 4.8 times that of the standard users. In a case in Shenzhen in 2022, the patient attended a pool party on the third day after surgery, and the concentration of pseudomonas aeruginosa in the water was 3 times higher than the standard, resulting in suppuration at the injection site. The bacterial culture showed that the number of colonies reached 10^6 CFU/mL, and finally the intravenous injection of ceftazidime took 14 days to control the infection, costing an additional 12,000 yuan in medical expenses.
According to a 2021 study in the Journal of Aesthetic Surgery, delayed anaphylaxis caused by crosslinker residue occurs 1.8% of the time, and most of the time occurs 90 to 120 days after injection. In a case in Beijing, a 35-year-old woman developed facial erythema on the 97th day after surgery, and the serum IgE detection value soared to 380IU/mL (normal value <100). Tissue biopsy showed that the density of CD4+ lymphocyte infiltration was 6 times that of normal skin, and it required 20mg/ day of oral prednisone for 28 consecutive days to be relieved.
Regarding filler displacement, a three-dimensional imaging study at Seoul National University in South Korea showed that the material injected into the superficial dermis moved down by an average of 1.2 mm per year. In a case in Chengdu in 2023, the prominent cheekbone of the patient caused the 0.6ml material injected to slip to the law line within 9 months, forming two obvious bumps. When repairing, the solution fee of 4500 yuan should be paid first and then injected again, the total cost increased by 65% compared with the first operation.
Make sure not to apply any or makeup products with irritating ingredients within a week after the procedure, and avoid cosmetics getting near the wound as this may cause an infection. Immediately contact your physician for treatment if any abnormal reaction happens, for example, intense swelling, inflammation, or an allergic reaction.
The effect of temperature on recovery is often overlooked, with data from Peking Union Medical College Hospital showing that postoperative exposure to more than 32 ° C can prolong the duration of edema by 40%. In the summer of 2020, a patient in Guangzhou immediately went to work in a high-temperature workshop after injection. The ambient humidity reached 85%, resulting in redness and swelling in the injection area for 21 days. Thermal imaging showed that the local temperature was 2.3℃ higher than that in the normal area, and finally resolved by six times a day icing combined with dexamethasone injection.
Quantification of risk in individuals with abnormal coagulation function showed that the area of postoperative bruising was 3.5 times greater in those with platelet counts below 150×10^9/L. In a case received by a hospital in Nanjing in 2022, a patient who concealed a long-term history of taking aspirin had a subcutaneous hematoma of 4×3 cm after surgery, the prothrombin time was extended to 16 seconds (normal 11-13.5 seconds), and the operation to remove the hematoma took 45 minutes, and the cost was 2800 yuan more than that of conventional operations.
Regarding differences in material metabolism, the University of California 2023 Gene Study found that those carrying the HAS2 gene mutation metabolized hyaluronic acid 58% faster. A consumer genetic test in Shanghai showed that its hyaluronidase activity was 2.1 times that of ordinary people, resulting in a unit price of 8800 yuan of filler only maintained for 4 months, and after switching to stimulative products containing PCL materials, although the single cost rose to 12,000 yuan, the effect lasted 16 months, and the annual maintenance cost fell by 34%.
The risk of injection level deviation can be reduced by ultrasound guidance, but the data show that 6% of the procedures still have errors due to insufficient image resolution. In 2021, an institution in Wuhan used an old ultrasound device (resolution 0.3mm), resulting in a 0.7mm deviation in injection depth, causing vascular compression, and the patient experienced throb headaches lasting 14 days. After upgrading to a 0.1mm resolution device, the incidence of similar accidents dropped to 0.8%.
Effect duration
The clinical follow-up of Shanghai Ninth People’s Hospital in 2023 showed that the average maintenance time of bijunction hyaluronic acid with a viscosity value of 50-60Pa·s was 9.2 months, while the validity of single-phase products was only 5.8 months. A 32-year-old woman in Hangzhou injected 1.2 ml of high-viscosity material and found through monthly three-dimensional imaging tests that 63% of the initial volume was still retained after 12 months, but only 28% of the control group using low-viscosity products during the same period. It is worth noting that the difference in cross-linking degree of different batches of the same brand will lead to a time fluctuation of ±15%, and in 2022, due to the low concentration of cross-linking agent, the validity period of a batch is shortened to 7 months, causing collective rights protection incidents.
Individual metabolic differences significantly affect the effect, South Korea’s Seoul National University genetic testing found that people carrying HAS2 gene rs2304689 mutation, hyaluronic acid metabolism rate increased by 41%. A consumer gene report in Beijing shows that its hyaluronidase activity is 1.7 times that of ordinary people, and the conventional product with a unit injection price of 6800 yuan is only maintained for 4 months, and after changing to the collagen-stimulated material containing polycaprolactone microspheres, although the single cost is increased to 9800 yuan, the effect is extended to 18 months, and the annual maintenance cost is reduced by 29%.
The level of injection has a significant impact on persistence, and three-dimensional ultrasound studies at Nanjing Medical University have confirmed that the annual displacement rate of materials injected in the upper periosteum is only 23% of that of the dermis. In a Wuhan case in 2021, doctors mistakenly injected 0.5 ml of material into the superficial layer of the dermis, and the volume loss reached 82% after 6 months, while the same dose of material injected into the periosteal layer lost only 37% during the same period. At present, the advanced mechanism adopts 22G blunt needle with 0.1 mm resolution ultrasonic guidance, which can control the level error within ±0.3 mm, and reduce the standard deviation of the validity period from 2.8 months in traditional operation to 1.2 months.
The influence of temperature environment is often ignored, and the joint analysis of Guangzhou meteorological data and medical and beauty institutions shows that in areas where the average annual temperature exceeds 22 ° C, the metabolic rate of filler is accelerated by 18%. In a case in Shenzhen, due to long-term exposure to 28℃ air conditioning environment, the degradation rate of subcutaneous materials in summer injection was 31% faster than that in winter injection, resulting in the original plan to maintain 10 months of effect disappeared 3.2 months earlier. Laboratory simulations show that every 1 ° C increase accelerates the activity of hyaluronic acid decomposition enzyme by 9%, which is the main reason why beauty seekers in tropical regions are 27% more frequent than those in temperate regions.
Exercise habits are strongly related to the durability of the effect, Shanghai Institute of Sport research found that people who do more than 150 minutes of high-intensity exercise per week, the speed of filler metabolism increased by 34%. A marathon enthusiast in Hangzhou ran 300 kilometers per month, and the material residue was only 39% after 6 months of injection, while the sedentary office population retained 61% in the same period under the same conditions. This is because the peak facial blood flow velocity during exercise can reach 4.2 times that of the resting state, accelerating the biodegradation process of the filler.
Skin thickness is positively correlated with maintenance time, and the data model of Peking Union Medical College Hospital shows that for every 0.1 mm increase in tissue thickness, the validity period is extended by 22 days. The preoperative ultrasound test of a beauty seeker in Chengdu showed that the skin thickness of 0.7 mm was maintained for 11 months after injection of 0.6 ml of material, while another customer with a thickness of only 0.3 mm was able to shorten the validity period to 6.5 months with the same dose. This explains why people with skin thickness of more than 1 mm can take 14 months to fill the second time, which is 114% more cost-effective than those with thin skin.
The cost performance calculation in the consumption decision shows that the selection of collagen-stimulated materials with a unit price of 12,000 yuan/ml, although the first cost is 80% higher than that of conventional products, the total maintenance cost can be saved by 42% in three years. The mathematical model established by an actuary in Hangzhou shows that under the constraint of a budget of 20,000 yuan, the “high unit price long cycle” scheme can obtain 7.3 months more effective time than the “low unit price short cycle” scheme, and the postoperative satisfaction score is increased by 19 percentage points.
Fill type
The viscosity value of bijunction hyaluronic acid is usually between 20-60Pa·s. Data from Shanghai Ninth People’s Hospital in 2023 show that the volume retention rate of products with a viscosity of 50Pa·s injected into the tear duct reached 68% after 12 months, while the volume retention rate of products with low viscosity (20Pa·s) was only 32% during the same period. In a case in Hangzhou, doctors mistakenly injected a high-viscosity material into the superficial dermis, resulting in a “indentation effect” lasting 21 days, which was eventually removed by three injections of lysozyme, costing an additional 40% of the original price. In contrast, the standard medium viscosity (35Pa·s) material achieved 91% customer satisfaction at deep injection.
The allergy rate of collagen fillers was as high as 4.3%, significantly higher than that of hyaluronic acid (0.9%). In 2022, a facility in Chengdu used bovine collagen products with a concentration of 30mg/mL, resulting in erythematous reactions in 5 customers, including 1 case whose serum IgE detection value soared to 550kU/L (normal <100), requiring antihistamine injection for 15 consecutive days. At present, the mainstream program turns to gene recombinant human collagen. Although the unit price is increased to 9800 yuan/branch, the probability of allergy is reduced to less than 0.3%, and the postoperative redness and swelling time is shortened by 62%.
The stimulation effect of poly-L-lactic acid (PLLA) has a lag, and the tracking data of Peking Union Medical College Hospital show that the collagen proliferation amount in 3 months after injection is only 38% of the final effect, and it takes 6-9 months to fully show the effect. In a case in Shenzhen in 2021, the beauty seeking patient did not see significant improvement 2 months after surgery, and arbitrarily added injections led to the formation of facial nodules, and the histopathology showed that the collagen fiber density exceeded the standard by 3 times, and the repair cost was 2.7 times that of the initial treatment. Laboratory data show that each bottle of PLLA needs to be redissolved with 5mL of sterile water and left for 24 hours to ensure that the particle distribution uniformity error is less than 15%.
The diameter range of hydroxyapatite (CaHA) microspheres is critical, and FDA-approved Radiesse products have a particle size of 25-45 microns. In 2023, a Shanghai institution used non-standard products (particle size 10-15 microns), resulting in granuloma in 6 customers. CT scan showed that the density of foreign particles reached 120 /cm³, and the removal operation took 4 hours/case. The calcium-phosphorus ratio of the compliant products is strictly controlled at 1.67 and must be used with lidocaine, otherwise the injection pain score (VAS) will increase from 3.2 to 6.8 out of 10.
The survival rate for autologous fat transplantation varies greatly, with thigh fat survival (54%) 18% higher than abdominal fat, according to a study by Guangzhou Medical University. In a case in Hangzhou in 2020, doctors used a 2.5mm diameter liposuction needle combined with 800rpm centrifuge for 8 minutes, and the final survival rate reached 63%, while the traditional method (3.0mm needle + static precipitation) was only 41%. However, the initial absorption rate of fat filling was as high as 40-60%, and a Beijing customer received two supplementary injections within 3 months to achieve the desired effect, with a total cost 220% higher than that of the hyaluronic acid program.
The penetration depth of the water-optical needle composite formula determines the effect. Dermoscopy observations at Seoul National University in South Korea showed that hyaluronic acid could be delivered to the middle dermis (1.2mm depth) using a 34G needle (0.18mm diameter), while needle rolling only reached 0.3mm. In 2022, an institution in Nanjing used non-standard needles (32G) in violation of rules, resulting in epidermal scabs in 12 customers, the measured injection depth error reached ±0.4mm, and the repair period was extended to 2.3 times that of routine. Normal operation requires the acceptance of 15-20 micropores per square centimeter of skin, and the density deviation of more than 20% May cause color deposition.
The degradation cycle of the new recycled material polycaprolactone (PCL) is as long as 24-36 months, but the injection amount needs to be strictly controlled. In the case of excessive injection in a clinic in Hangzhou in 2023, 0.8mL of products containing PCL microspheres were injected into unilateral lacrimal furrows. After 6 months, 0.6cm³ hard mass was formed due to collagen hyperplasia, and the final surgical resection cost 18,000 yuan. Laboratory data show that the number of microspheres per milliliter of PCL products should be controlled at 300,000-500,000, and the concentration deviation of more than 10% will significantly increase the risk of complications.
Postoperative care
A 2023 study by Shanghai Ninth People’s Hospital showed that for every 1-hour delay in ice application within 24 hours after surgery, the duration of edema was extended by 18%. In a case in Hangzhou, the swelling volume of the patient reached 3.2cm³ 48 hours after surgery due to delayed ice treatment, which was 2.7 times that of the standard ice treatment group (every 2 hours and 15 minutes), and eventually spent 1,200 yuan more to buy swelling reduction needles. The correct approach is to use a 4℃ medical cold compress, replace it every 2 hours, and the swelling subside speed will increase by 41% for 3 consecutive days.
Regarding cleaning norms, data from Guangzhou Medical University show that the use of medical facial cleansers with a pH of 5.5-6.0 can reduce the infection rate from 7.3% to 1.8%. In 2022, a patient in Shenzhen misused skin care products containing hydroxic acid (pH3.2), resulting in the expansion of the scab area at the injection site to 1.5cm², the repair period to 28 days, and the cost of medicine was 3,600 yuan more than the standard care. It is recommended to rinse with warm water with a flow rate of < 15L/min within 7 days after surgery, and the water temperature is strictly controlled at 32-34℃.
Sleep position has a significant impact. Three-dimensional scans at Peking Union Medical College Hospital showed that supine position had a 63% lower material displacement rate than lateral position. In a case in Chengdu, the patient slept on the right side for 5 consecutive days after surgery, resulting in the displacement of the filler to the left side by 1.8mm, and the cost of asymmetric repair reached 75% of the original price. It is recommended to use a 45 degree tilt pillow with a neck pressure of < 25mmHg for 14 consecutive days.
Dietary control needs to be accurate to the milligram level, the Journal of Cosmetic Surgery study confirmed that sodium intake of more than 2000mg per day will increase the probability of edema by 2.4 times. In a case in Nanjing in 2023, the patient consumed hot pot containing 3800mg of sodium after surgery, causing facial swelling that lasted for 9 days, and was finally relieved by intravenous injection of furosemide 20mg/ day. Standard diet should control sodium intake below 1500mg/d, and supplement 200mg vitamin C to promote capillary repair.
In terms of exercise restriction, the Seoul National University study found that the heart rate of more than 120 beats/minute 72 hours after surgery accelerated filler metabolism by 17%. A fitness coach in Hangzhou conducted HIIT training on the second day after surgery, resulting in the material with a unit price of 8800 yuan to degrade 3.2 months in advance, and the average annual maintenance cost increased by 42%. It is recommended that the walking speed be less than 4km/h for 7 days after surgery, and the alarm threshold set by the heart rate monitoring bracelet is 110 times/min.
Sun protection measures directly affect the probability of color sink, Guangzhou meteorological data correlation analysis shows that when the UV index > 5 unprotected exposure for 1 hour, the incidence of color sink increased to 31%. In a case in Sanya in 2021, the patient was active in an environment with UV index 8 for 2 hours 3 days after surgery, causing 0.6cm² brown plaques, and the laser freckle treatment cost 9,600 yuan for 6 times. Use a physical sunscreen with SPF50+ and PA++++. Apply at least 2mg per square centimeter of skin and reapply every 3 hours.
Drug contraindications are often ignored. Statistics from Beijing 301 Hospital show that the bruise area of patients taking ibuprofen after surgery is 2.3 times that of the standard medication group. In a case in Wuhan in 2022, a patient took 600mg of ibuprofen without authorization to relieve pain, causing a 4×3cm hematoma, prothrombin time extended to 16 seconds (normal 11-13.5 seconds), and the removal operation took 47 minutes, and the cost increased by 2,800 yuan.
The most common mistake is expression management, the University of Tokyo myoelectric study showed that frequent laughter in the first seven days after surgery will make the orbicularis eye muscle contraction frequency of three times the normal value, resulting in a 29% higher risk of material displacement. In 2023, a Hangzhou anchor laughed continuously for 6 hours on the day after surgery due to work requirements, causing the filler to shift to the cheekbone, and the amount of lysin used in repair exceeded the standard dose by 23%, resulting in an additional cost of 1,600 yuan. It is recommended to use muscle relaxation patch to assist in limiting facial muscle activity, and wear it for more than 18 hours a day.
Cost range
The Shanghai Ninth People’s Hospital’s 2023 price list shows that the price range of domestic hyaluronic acid fillers per milliliter is 3800-6800 yuan, while imported brands such as Qiao Yadon can reach 8800-12800 yuan. However, the actual expenditure often exceeds the budget – in a case in Hangzhou, the United States found bilateral asymmetry after the injection of 1.2 ml, made up 0.3 ml correction, and the total cost was 43% higher than the first offer. Laboratory data show that for every 10% increase in cross-linking degree, the unit price of the product increases by 18%, but the annual maintenance cost can be reduced by 26%.
The regional price difference is amazing, the average price of tear groove filling in Chengdu medical beauty market is 6,500 yuan/side, while the median charge for the same project in Shanghai is 9,800 yuan. The 2022 “China Medical Beauty Industry Development Report” pointed out that the doctor technical fees of high-end institutions in first-tier cities accounted for 58% of the total costs, which is 2.3 times that of institutions in third-tier cities. For example, a chief doctor in Beijing costs 4,000 yuan for a single injection, while general doctors only 1,200 yuan, but the former postoperative repair rate is as low as 3.7%, the latter is 19%.
Complications management is a major area of hidden expenditure. Statistics from a Guangzhou institution show that about 12% of beauty seekers need to pay additional lyolytic enzyme fees (800-1500 yuan/time), of which the average treatment cost of vascular embolism cases is 23,000 yuan. In 2023, due to the displacement of a patient in Shenzhen, the cumulative cost of three repairs was 47,000 yuan, which was 3.8 times the initial cost. If the cost of missing work is calculated (average daily income of 500 yuan), the hidden loss of 21 days in the recovery period reaches 10,500 yuan.
Promotion traps need to be vigilant, the 2023 double 11 data of an e-commerce platform shows that 37% of the orders of “tear hole filling package” priced at 5,980 yuan were induced to upgrade products, and the actual payment average reached 8,230 yuan. More hidden is that a clinic in Hangzhou mixed 1 ml of regular products with 0.5 ml of parallel goods, and when it was investigated by the drug regulatory department, the cross-linking degree deviation of the involved fillers reached 28%, and the cost of patient rights protection exceeded 10,000 yuan.
Long-term maintenance costs vary significantly, with a five-year tracking report by South Korea’s LG company showing that using collagen-stimulated materials with a unit price of 12,000 yuan/ml averaged 6,800 yuan per year, while conventional hyaluronic acid solutions cost 11,000 yuan per year. A model established by an actuary in Beijing shows that the selection of long-acting materials with a budget of 30,000 yuan can gain 14 months more effective time than short-acting products, and the cost performance is increased by 39%.
Additional service fees are often the focus of controversy, a Nanjing institution will be 200 yuan/time postoperative cold compress forced packaging sales 10 times, the actual market price is only 80 yuan/box. What is more, in 2022, a clinic in Chengdu charged a “stereoscopic imaging design fee” of 3,800 yuan, but the 3D simulation software used was actually an open source system modification, and the cost was less than 200 yuan. Industry surveys show that hidden fees can inflate total spending by 18-25%.
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