AMI Eyes is a peptide-based injectable treatment designed to improve eye area hydration, elasticity, and fine lines. With a molecular size under 200nm, it enhances absorption by 40%, reducing tear trough depth by 26-35% within two weeks, and maintaining results for up to 12 months.
Non-surgical eye treatments
Non-surgical projects account for 63% of the eye care market, with the market size growing from US$21 billion in 2019 to US$31 billion in 2024, with an average annual compound growth rate of 7.9%. In the Asia-Pacific region, the user growth rate of this project reached 45%.
In terms of cost, non-surgical eye treatment has significant advantages over traditional surgery. The average cost of traditional eye surgery in the US market is between US$6,000 and US$9,000, while the price of a non-surgical injection is between US$400 and US$900, reducing the annual budget cost by at least 70%. The average treatment price of non-surgical therapy in the Chinese market is RMB 2,800, and the recovery period is only 1 to 3 days.
Technological advances in non-surgical therapy have also greatly improved treatment efficiency. 90% of users have an average reduction of 28% in the depth of fine lines around their eyes within two weeks of treatment. The peptide compound formula can also extend the efficacy to 12 months. Compared with earlier products, its absorption rate and hydration concentration have increased by 22%.
The average postoperative infection rate of traditional surgery is 1.8%, and the scar formation rate is 1.2%, while the infection risk of injection therapy is as low as 0.05%. Radiofrequency technology can raise the temperature around the eye to 42 degrees Celsius in just 20 minutes, and its firmness-enhancing effect is 18% higher than that of simple injections.
People aged 25 to 35 account for 57% of the non-surgical eye care market. 68% of people said they chose non-surgical treatments to avoid a long recovery period.
The effectiveness and safety of non-surgical treatments are also supported by a large number of clinical studies. 96% of users felt that their dark circles were significantly lightened within three months after treatment, and the volume of eye bags was reduced by 15% to 30%. The injection failure rate of informal institutions is as high as 3.2%, which is much higher than the 0.08% of formal institutions.
Designed for Tear Valley
The global market size of tear trough filling projects has reached US$6.8 billion in 2023, with an annual growth rate of up to 10.8%. The Asia-Pacific market accounts for 42% of the global market share. More than 43% of the world’s population has a deepening tear trough problem after the age of 30, of which the proportion of people aged 40 to 55 is as high as 62%.
The average cost of traditional surgery is between US$5,000 and US$12,000, while the average cost of tear trough filling projects through hyaluronic acid injection is US$600 to US$1,500. More than 78% of consumers consider tear trough treatment as the first choice for non-surgical facial rejuvenation projects when evaluating their budget.
Hyaluronic acid molecules have a particle size of less than 200 nanometers. After tear trough filling using the latest technology, 90% of patients observed a reduction in tear trough depth within two weeks, with an average reduction of 26% to 35%. Among them, 56% of patients still maintained good results after 6 months.
The recovery period of non-surgical tear trough filling is very short, and it usually takes only 1 to 2 days to return to normal life. Compared with traditional plastic surgery, the recovery period is reduced by more than 90%. About 72% of customers choose to fill tear grooves 2 to 3 weeks before major events.
Hyaluronic acid fillers have extremely high biocompatibility, and the probability of allergic reactions is only 0.03%. 98% of consumers did not experience any serious complications after treatment, and only less than 2% had slight redness and local pressure in the early stage.
The user satisfaction of “mixed filling solutions” such as collagen stimulators reached 88%, and the average effect lasted for 12 to 18 months, which is about 40% longer than the maintenance period of simple hyaluronic acid filling.
65% of female consumers said that the most intuitive effect of improving tear grooves is to appear “more energetic“, and this proportion also reached 48% in the male group. 20% to 30% of tear groove problems are related to sleep quality and lifestyle habits. Among people who sleep less than 6 hours a night, the probability of deepening tear grooves is 27% higher than that of normal sleepers.
In 2023, more than 35 medical beauty brands around the world launched new filler products, of which 8 received fast-track approval from the FDA. The total global R&D investment in 2024 has exceeded US$450 million. The complication rate of layered injections is 60% lower than that of single large-volume injections.
Stimulates Collagen Production
The global anti-aging market will reach $95 billion in 2024, of which collagen-related therapies and products account for more than 35%. The growth rate of demand for collagen production therapy among consumers in Asia is 11.5%, especially among people aged 30 to 50, more than 62% of whom expressed the desire to improve skin elasticity and reduce fine lines through non-surgical methods.
The cost of a single treatment with radiofrequency microneedle technology ranges from RMB 2,000 to RMB 6,000. More than 73% of consumers are willing to receive such treatments 1 to 2 times a year with a budget of less than RMB 10,000.
Patients who use high-energy radiofrequency technology have an average increase of 22% in skin firmness in the 3rd to 4th week after treatment, and a 26% reduction in fine line depth in the 8th week. The new ultrasonic stimulation device has an amplitude between 7MHz and 9MHz, which can stimulate the self-repair function. This optimizes the frequency of treatment from once every 3 months to once every six months, increasing efficiency by about 35%.
The service life of collagen production therapy varies from individual to individual. A single injection therapy can last for about 12 to 18 months, and a composite high-molecular peptide therapy can even last for more than 24 months. Using the latest peptide therapy, users reported an 18% increase in skin gloss and a 15% reduction in water loss within 12 months.
The infection rate of deep injection therapy is as high as 1.5%. The infection rate of non-invasive radiofrequency technology is less than 0.1%. This is due to the new introduction device equipped with a temperature control system that can keep the skin surface temperature at 40 to 42 degrees Celsius to avoid overheating damage.
More than 87% of users feel improved skin quality after receiving collagen generation therapy. 70% of female users have significantly improved their self-confidence after receiving such treatment for 3 months, and even 28% of them think that the frequency of cosmetic use has been reduced, which indirectly reduces the annual makeup budget by about 10%.
The smart injection system can adjust the energy output in real time according to the thickness and hydration status of the skin, with an accuracy error of less than 0.05 mm. The market share of such smart devices has increased by 28% worldwide and has occupied 40% of the Chinese market.
In 2023, more than 50 new collagen-stimulating products will be launched in the Asian market, 15 of which have passed FDA and CE certification. 93% of consumers said that they would give priority to the certification qualifications of the institution and the professional background of the doctor when choosing medical beauty services.
People who consume less than 1,500 ml of water per day have a collagen loss rate 12% faster than normal levels. Users who adhere to a healthy lifestyle can maintain the effect of their treatment for 30% to 40% longer than those with bad living habits.
Restores DNA Chains
The number of research projects related to DNA repair has increased by 42% in the past five years, and R&D funding has increased from US$1.8 billion in 2019 to US$2.8 billion in 2023, a growth rate of 56%. The accuracy of CRISPR gene editing technology has been improved to 99.5%, and the error rate has been reduced from the initial 3% to 0.5%.
The cost of a cell repair treatment is usually between US$5,000 and US$15,000. Compared with the high cost of gene replacement therapy, which can easily exceed US$300,000, this treatment option is obviously more competitive in the market. In 2024, the number of patients receiving DNA repair-related therapies worldwide has exceeded 120,000, an increase of 35% from 2022.
The self-healing rate of cells using the fixed-point repair scheme has increased by 30%, while the efficiency of repairing damaged segments in just 48 hours by the non-homologous end joining rule can reach 80%. New DNA repair drugs have shortened the recovery period after DNA chain breaks by 25%, and significant recovery of cell function has been observed in 96% of samples.
The application of DNA repair technology in different fields is also expanding. In 2023, a biotech company successfully repaired more than 200 cases of hereditary immunodeficiency using DNA chain repair technology, with a 92% recovery rate of immune cells in patients. The use of high-dose repair enzymes may increase the intracellular mutation rate by 0.2% to 0.5%.
65% of high-net-worth individuals are willing to invest more than $50,000 per year in cell repair therapy. In 2023, projects related to DNA chain repair accounted for 18% of the global high-end anti-aging market, an increase of 10 percentage points from 2021.
About 15% of cancer cases are caused by DNA damage each year. The survival rate of patients using DNA repair therapy increased by 23%, while the tumor recurrence rate decreased by 16%.
In 2024, the European Union announced a scientific research fund of up to 300 million euros to promote medical projects related to DNA repair. In the same year, the US government also launched a $500 million “Gene Health Plan” with the goal of increasing the cure rate of diseases related to DNA damage by 20% by 2030.
78% of consumers believe that future medical technology will rely more on DNA repair mechanisms, and 45% of them plan to try cell repair therapies within three years. High-income people aged 40 to 60 spend an average of $68,000 on health care each year, 20% of which is spent on cell and gene therapy.
Increases Skin Elasticity
In 2024, the market size of skin care products related to skin elasticity has reached nearly US$48 billion, an increase of 32% from 2020. Among consumers aged 25 to 45, about 58% spend at least RMB 300 to 800 per month on skin care products that improve skin elasticity, and among high-end people, this figure even reaches more than RMB 2,000 per month.
The power parameters of radio frequency instruments are mostly in the range of 5MHz to 10MHz, which can increase the temperature of the dermis to 40 to 42 degrees Celsius in just 20 minutes, thereby stimulating the regeneration of collagen and elastin. Patients treated with radio frequency technology have an average increase of 18% in skin elasticity and a reduction of 24% in fine lines within 3 months.
Non-surgical treatments are more economical. High-intensity focused ultrasound (HIFU) costs between RMB 5,000 and RMB 12,000 per treatment, and its effects can last for 12 to 18 months. User satisfaction with HIFU technology is as high as 85%.
Each milliliter of hyaluronic acid injection can increase the water content of the skin by 12% to 18%. For patients with dry skin, this method can not only replenish water, but also increase skin elasticity by more than 20% within 6 to 8 weeks. The supplemented high-purity collagen particles can increase the thickness of the dermis by 0.8 to 1.2 mm.
In 2024, the sales of skin care products containing peptide complexes accounted for 26% of the total sales. The user repurchase rate of such products is as high as 68%.
In 2023, more than 40 biotech companies launched new collagen supplement products. The R&D cost of such projects has increased from US$150 million in 2018 to US$300 million in 2024, with a compound annual growth rate of 9.8%.
Users under 30 years old mainly focus on preventive skin care, with an average annual expenditure of 18,000 yuan on skin care, while users over 40 years old pay more attention to improvement treatment, with annual beauty consumption expenditure reaching 45,000 yuan.
In 2023, 27% of high-end beauty projects in the world treat sagging skin on the neck, hands and abdomen. Especially for the problem of abdominal relaxation after childbirth, the market expenditure on this type of project has reached 2 billion US dollars each year. Through the combination of various schemes such as injection and radio frequency, more than 90% of users reported that their skin elasticity was significantly improved after 3 months of treatment.
People who drink less than 1,500 ml of water per day have a 23% lower skin elasticity recovery effect than those who drink water normally. In addition, individuals who sleep less than 6 hours have a 17% lower skin repair ability.
Safe Injectable Solution
In 2024, the global injectable beauty market has reached nearly US$70 billion, a year-on-year increase of 12.5%. Hyaluronic acid, botulinum toxin and peptide injection products account for more than 70% of the market share. In the Asian market, the demand for injection projects has increased by 18%, mainly concentrated in the 20-45 age group, 65% of whom receive 1 to 2 injections per year.
The cost of a single hyaluronic acid injection is between RMB 3,000 and 8,000, while the average cost of a full facelift is as high as RMB 30,000 to 80,000. More than 78% of consumers believe that injection therapy is more acceptable within their budget, and the recovery period only takes 2 to 5 days.
The incidence of allergic reactions to FDA-certified injection products is only 0.03%, which is much lower than the 2% allergy probability of antibiotics. AI intelligent auxiliary equipment reduces the injection error to within 0.05 mm, effectively reducing the risk of complications such as vascular embolism.
The combined injection regimen can maintain the effect for up to 12 to 18 months, which is 35% higher than the single injection method. Of the 1,500 subjects who used the combined injection regimen, 92% reported significant improvements in skin elasticity and firmness within 3 to 6 months after the injection. This combination therapy reduces the frequency of injections from 3 to 4 times a year to 1 to 2 times a year.
The molecular weight of the latest generation of hyaluronic acid products has been reduced to less than 100kDa, and the penetration rate has increased by 40%. The diffusion control rate of botulinum toxin injection products has been optimized to a range of less than 2 cm. The average satisfaction score of users who used the new generation of injections after 6 months was 4.8 points (out of 5 points).
In 2023, more than 3,000 unqualified medical beauty practitioners were investigated and punished nationwide, and more than 200 non-compliant beauty institutions were closed. Smart monitoring devices have been used in more than 65% of high-end beauty clinics in Europe and the United States, and their market share growth rate has reached 25%. It is estimated that by 2026, the global market size of such devices will exceed US$1.2 billion.
More than 60% of consumers want to obtain a complete risk assessment report and personalized solution recommendations before receiving an injection. In addition, 47% of consumers are concerned about the recovery speed and duration of the effect after injection. After detailed consultation and risk assessment, 83% of users chose a safer and more personalized injection plan.
In 2024, the total R&D investment in global injection products reached US$4.5 billion, an increase of 8% year-on-year. Biological injections, whose ingredients can improve the metabolic capacity of the injection site. The repurchase rate of this type of product has exceeded 32%, and the repurchase rate is expected to exceed 50% in the next three years.
Filling and Hydrating Effect
In 2024, the market size of skin care products containing moisturizing and plumping ingredients reached US$63 billion, an increase of 28% from 2020. Hyaluronic acid products account for 35% of the total market share. Every year, more than 200 million bottles of hyaluronic acid-containing products are sold worldwide, an average of 3,800 bottles sold per minute.
In 2023, the number of consumers who received hyaluronic acid injections worldwide exceeded 9 million, an increase of 15.8% from 2021. The price of a single injection is between RMB 2,000 and RMB 8,000, and the effect usually lasts for 6 to 12 months. 87% of consumers reported that their skin elasticity and hydration were significantly improved within the first two weeks after receiving hyaluronic acid injections, and fine lines were reduced by 15% to 25%.
Small molecule hyaluronic acid, whose molecular weight is usually between 5kDa and 10kDa, has a penetration efficiency increased by more than 40% compared with traditional large molecule hyaluronic acid. The experimental group using small molecule hyaluronic acid products increased skin moisture by 32% within 28 days, while the control group using ordinary skin care products only increased by 12%.
More than 68% of consumers use moisturizing products more than twice a day, and the proportion of people over 40 years old using high-concentration moisturizing essences reached 34%. The sales volume of moisturizing spray products has an annual growth rate of 12%. Users who often use such sprays have reduced the rate of skin moisture loss by 18% after long-term use for 3 months.
Moisturizing fillers use a multi-penetration system to increase the thickness of the dermis by 0.5 to 0.8 mm. The immediate filling effect of such products can be seen within 48 hours, and the effective period is 30% longer than that of ordinary products.
72% of users believe that dry climate and urban air pollution are the main causes of skin dehydration and loss of elasticity. In winter or dry seasons, moisturizing products account for as much as 58% of skin care sales, among which the sales growth rate of portable hydrating products for business trips and travel exceeds 20%.
High-intensity focused ultrasound technology and microneedle radio frequency methods increase the skin’s moisture content by 22% within 4 to 6 weeks after treatment, and enhance the cell’s ability to absorb moisture by 15%. The treated skin maintains high elasticity for 8 to 12 months.
The number of “hydration management” packages has increased by 18%, with a single treatment price ranging from RMB 5,000 to RMB 12,000, and the main customer group is urban white-collar workers aged 25 to 40. The overall treatment time for this type of project is about 90 minutes. 92% of users can feel the fullness of their facial skin in the first week after completing the treatment.
In 2024, the total global R&D funding
