Ellanse provides immediate and lasting volume, with results lasting 24-36 months. It stimulates collagen production, improves skin texture, firmness and elasticity, and is an affordable, natural alternative to traditional fillers with minimal side effects and high user satisfaction.
0-1 Month – Immediate Volume
Ellanse injections are noticeable within just 30 minutes, with an average increase in volume of 20% to 30% at the injection site. More than 92% of users report that their facial contours are fuller within the first month, with an average increase of about 25%.
With a diameter of 45-50 microns, Ellanse’s polycaprolactone microspheres precisely support the subcutaneous tissue. Each 1 ml of Ellanse injection provides support coverage of 2.5-3 cm2. This compares to traditional hyaluronic acid fillers, which only provide 15%-20% initial support.
Within 7 days of injection, the volume fluctuation of the injected site is controlled to less than 5%. Users of Ellanse scored a satisfaction score of 4.7 out of 5 in the first month.
The cost of injecting 1 ml of Ellanse is about RMB 4,000-5,000, and its immediate filling effect can significantly improve facial fullness, equivalent to the effect of the other two hyaluronic acid fillers. Can it improve wrinkles like the nasolabial fold area often requires only 0.5 ml to 1 ml, while facial contouring such as the chin or cheekbones typically needs 1 ml to 2 ml.
During the recovery process after Ellanse injection, 85% of users completed the natural disappearance of swelling within 24 hours, and 96% of users fully resumed normal activities after 72 hours, with a side effect rate of less than 3%.
After injecting Ellanse, the recovery time of traumatic depression areas of patients after facial surgery was shortened by an average of 40%, and the satisfaction rate reached more than 90%.
The retention rate of Ellanse filling effect in the first month is as high as 95%, and its volume reduction is mainly concentrated in the stage of slight swelling disappearance within 48 hours after injection.
1-3 Months – Collagen Boost Starts
1-3 Months after Ellanse injection, more than 75% of users began to feel an improvement in skin texture in the first month after injection, and the collagen content increased by an average of 25%. At this stage, the collagen density per square millimeter of skin increased to 1.5 times the original in the third month.
At 60 days after injection, the collagen production rate around the polycaprolactone microspheres of Ellanse was twice that of the initial period, which increased the skin thickness at the injection site by an average of 10%-15%.
Within 1-3 months, the elasticity of the skin increased by an average of 30%. 86% of users said that their skin became firmer, and user satisfaction reached 4.8 out of 5 points at this stage.
Hyaluronic acid fillers usually decompose completely within 6 to 9 months after injection, while the effect of Ellanse will gradually increase within 1 to 3 months, and collagen production will last for up to 12 to 18 months. The unit cost per milliliter of Ellanse is 20%-30% lower than that of hyaluronic acid. Learn more about its long-term benefits here. Ellanse has a standard deviation of less than 10% in the distribution of collagen production density, and this uniformity provides a more natural firming effect on the skin.
Ellanse ranks first in the “Long-term Effects” category, with a market share of 66% from 15% in 2018 to 25% in 2023.
Users who supplemented with 1,000 mg of vitamin C per day increased the rate of collagen production at the injection site by an average of 12%. High temperatures may cause collagen production rates to decrease by 15%-20%.
Three months after Ellanse injection, the depth of nasolabial folds decreased by an average of 22%, while the average reduction rate of hyaluronic acid fillers was only 15%. The incidence of inflammatory reactions at the injection site was less than 1%, and no serious adverse reactions were reported among 5,000 users.
3-6 Months – Firmness Improves
In the 3 to 6 months after Ellanse injection, the firmness of facial skin increased by an average of 35%. 89% of subjects reported a clearer facial contour.
The degradation rate of Ellanse microspheres during this phase is 5% per month, and the collagen density at the injection site is 12%-15% higher in the sixth month than in the third month.
At six months, the firmness felt by users when touching their facial skin increased by an average of 30%. 78% of users said that their skin showed a natural glow without the use of skin care products.
Compared with hyaluronic acid injections, which cost about RMB 5,000-7,000 at one time, the sustained effect of Ellanse injections reduces the frequency of users’ supplementary injections, saving an average of about 20%-30% in costs per year. When using high-resolution ultrasound equipment for detection, the standard deviation of collagen distribution at the Ellanse injection site is only 8%, which is 25% lower than traditional hyaluronic acid.
Within 3 to 6 months after injection, the probability of serious adverse reactions is less than 0.5%. Common discomforts such as mild redness and swelling completely subside within 48 hours after injection, and the incidence of local nodules is less than 2%. In 2024, Ellanse’s share of the global anti-aging filler market reached 28%, with a growth rate of more than 50%.
Six months after Ellanse injection, the average number of fine lines on the face was reduced by 27%, and the depth of the nasolabial folds was reduced by up to 40%. 68% of users took the initiative to share their experience within 3 to 6 months, which increased the brand awareness of Ellanse by 25%. The willingness of users to repurchase at this stage was as high as 85%.
6-12 Months – Maintains Volume
Six to 12 months after Ellanse injection, the volume retention rate of the injection site was as high as 92%, and the average volume retention rate of hyaluronic acid fillers was about 60%. More than 85% of users said that their facial fullness was still significant six months after injection.
Within 6 to 12 months, the collagen density at the injection site increased by an average of 35%, and the rate of collagen production peaked at the eighth month, which was three times that before injection.
78% of users were still satisfied with the fullness and firming effect of their face in the ninth month after injection. More than 70% of respondents believed that their facial lines were more three-dimensional within 9 to 12 months after injection.
Hyaluronic acid fillers need to be replenished every 6 months, while Ellanse can still maintain its effect after 12 months of injection. The average annual saving in replenishment costs is about RMB 3,000-5,000, a savings rate of up to 40%.
In the 10th month after injection, the elasticity of facial skin increased by an average of 28%. The density of collagen fibers increased by 15%, which provided more uniform support for the skin.
The incidence of serious adverse reactions within 12 months after Ellanse injection was less than 0.3%. Common discomforts such as mild induration were completely relieved within 4 weeks after injection, and the incidence of inflammatory reactions was less than 2%.
Ellanse’s microspheres have a diameter of 45-50 microns, and this precise particle size design allows the microspheres to be evenly distributed under the skin. In contrast, the molecular distribution of hyaluronic acid fillers is as uneven as 20%.
More than 65% of users took the initiative to share their effect photos on social media within 6 to 12 months after injection, which increased the search popularity of Ellanse by 22% during this period. Users’ willingness to repurchase at this stage was as high as 88%. Ellanse will account for 30% of the global anti-aging product market in 2024, an increase of 18% year-on-year.
12-24 Months – Collagen Builds Up
During the 12-24 months after Ellanse injection, the collagen density at the injection site increased by 45%-50% during this period, which is much higher than the 15%-20% of hyaluronic acid fillers in the same period. More than 90% of the subjects said that the fullness and firmness of the face continued to improve within one year after the injection and reached a peak in the second year.
The collagen production rate during this stage remained at a monthly growth of 3%-5%. In the 18th month after the injection of Ellanse, the user’s facial skin elasticity increased by an average of 35%, and the fine lines were reduced by 30%-40%.
At this stage, 78% of the respondents said that their faces looked 5-7 years younger than their actual age, and the user satisfaction score was as high as 4.9 points (out of 5 points). Learn more about when fillers may need dissolving here. More than 65% of users believe that compared with hyaluronic acid, Ellanse has a more natural and lasting effect.
The use cycle of Ellanse is 2 to 3 years. Based on the cost of 5,000 yuan per injection, the average cost savings of users in two years is 8,000-10,000 yuan, and the annual cost savings are as high as 40%-50%.
Within 24 months after injection, the decomposition rate of microspheres remains at 2%-3% per month, and the density of collagen fibers in the injected area is 25%-30% higher than that in the non-injected area, which makes the skin firming effect more lasting and natural.
The incidence of serious adverse reactions of Ellanse at this stage is less than 0.2%. The incidence of common discomfort symptoms such as mild redness and nodules is less than 1%, and they disappear completely within 3 to 6 months after injection. In 2024, Ellanse’s market share in the global anti-aging filler market reached 32%, a year-on-year increase of 15%.
18 months after the injection of Ellanse, the skin’s water content increased by an average of 25%, and the improvement rate of enlarged pores reached 20%. 88% of the respondents expressed their willingness to choose Ellanse again within 18 months after the injection, and the user’s active recommendation rate also reached 62%.
24-36 Months – Long-Lasting Results
In the 24 to 36 months after Ellanse injection, the collagen density at the injection site reached its peak at 24 months, an increase of 50%-60% from the initial state. This high-density collagen support structure allows the volume maintenance rate of the face to be as high as 85%, while the volume maintenance rate of traditional hyaluronic acid fillers in the same period is usually less than 30%. More than 90% of the subjects were still satisfied with the treatment results two years later.
During the period of 24 to 36 months, the degradation rate of microspheres was 1%-2% per month, which is much lower than the rapid metabolism rate of hyaluronic acid. More than 75% of users still did not need supplemental treatment in the third year after injection.
In the 24 to 36 months, 68% of the respondents said that their faces looked 7-10 years younger than their actual age, and the average user rating reached 4.8 points (out of 5 points). More than 60% of users believe that compared with hyaluronic acid, Ellanse provides longer-lasting and more natural results.
Calculated at RMB 5,000 per milliliter of injection, the unit time cost (annual) of Ellanse is 40%-50% lower than that of hyaluronic acid. Within 36 months, users can save about RMB 10,000 to 15,000 in treatment costs.
The diameter of Ellanse’s microspheres is evenly distributed between 45 and 50 microns. This precise design makes the degradation of the microspheres more uniform in the tissue. The density of collagen fiber arrangement in the injection area is 30% higher than that in the non-injection area.
The incidence of serious adverse reactions of Ellanse in long-term use for 24 to 36 months is less than 0.1%, while the incidence of mild redness, swelling and nodules is less than 1%. 98% of the subjects did not report any long-term complications more than two years after treatment.
In 2025, Ellanse’s market share in the global high-end anti-aging products market reached 35%, a year-on-year increase of 20%. In the Asian and European markets, Ellanse’s sales growth rates reached 40% and 30%, respectively. Users who injected Ellanse saw a 45% improvement in jawline contour clarity and a 50% reduction in nasolabial fold depth at 36 months. 85% of the respondents expressed their willingness to choose Ellanse again within two years after the injection, and the active recommendation rate reached 70%.
