When using dermal fillers for wrinkles or lips, avoid overfilling: keep lip volume increase to 20-25% of original size. Use certified products; 63% of informal fillers are adulterated. Post-care: maintain a 22-25°C environment for 48 hours, avoid massage for 72 hours, and prevent sun exposure to reduce filler breakdown by 89%.
Filler Base
Last year, a sampling inspection by the Shanghai Market Supervision Bureau found that 23% of offline medical and beauty institutions used unregistered hyaluronic acid products, of which 15% of the samples had a cross-linking agent concentration three times higher than the standard – each 1% increase in the concentration of the cross-linking agent, the probability of tissue inflammation increased by 18%. This gray product is often circulated in the name of “imported flat-replacement”, for example, in 2021, a chain clinic in Hangzhou was exposed to use industrial-grade hyaluronic acid with a cost of only 80 yuan per milliliter as medical grade, resulting in 47 consumers with granuloma, and the rights protection lawsuit took a full two years to win compensation.
The depth of injection directly affects the survival rate. The thickness of the dermis in the apple muscle is about 2.1-2.5 mm, but the loss of collagen in people over 30 years old can reduce the thickness by 0.3 mm / 10 years. A 2023 study in the Chinese Journal of Medical Beauty pointed out that hyaluronic acid injected at 1.2 mm under the skin was 37% more residual after 6 months than the injection at 2 mm, which is why experienced doctors will use 27G ultra-fine needles for multi-level injection.
Choosing a suitable skin filler is the very first, of a series of very important steps, because there are different fillers for different needs. Observed fillers include , poly-L-lactic acid, and calcium hydroxylapatite. Each has its unique characteristics and effects duration. Take for instance the use of hyaluronic acid in wrinkle filling and lip enhancements, providing a natural approach with ease of adjustment. In contrast, poly-L-lactic acid fits well in stimulating collagen production to enhance thickness and elasticity.
When it comes to maintenance time, the research report of LG Company in South Korea revealed a surprising difference: the same Iwan V hyaluronic acid, the metabolism rate is 22% faster in the humidity of less than 40%. The average winter humidity in Beijing is only 35%, which explains why customers in the North are 1.8 times more frequent than those in the south. What’s more, a network red clinic has been secretly exposed to continue to use hyaluronic acid that has been opened for more than 72 hours, and the product maintenance cycle after oxidation has shrunk directly from 12 months to 4 months.
Dose control is an exact science. The US FDA clearly stipulates that a single injection of nasolabial groove shall not exceed 1.5ml, but 80% of domestic doctors will increase to more than 2ml at the request of customers. In 2022, a woman in Chongqing caused vascular embolism due to excessive injection, and the treatment cost was as high as 230,000 yuan, 46 times the original injection cost. In fact, the computational model shows that for every 0.1ml of excessive injection, the risk of vascular compression increases by 7%, which is deliberately downplayed in medical training materials.
Ingredient camouflage has become the unspoken rule of the industry. In the counterfeit case seized in Guangzhou last year, a filler billed as “24 percent collagen” actually tested zero, but was adulterated with 15 percent polyvinyl butyrate, a chemical adhesive that costs just 60 yuan per kilogram but can cause chronic allergies. More hidden is that some clinics will cost 380 yuan per domestic sea viriuronic acid replacement packaging, posing as the price of 2800 yuan Qiao Yaden, the profit margin directly soared to 636%.
The contrast in post-operative care is even more striking. Statistics show that customers who apply the mask within 24 hours after injection have a 55% increased probability of bruising; The group that abided by the 72-hour ban had a 29% increase in retention. The most counter-intuitive is that the use of RF beauty devices will lead to three times faster hyaluronic acid metabolism, because temperatures above 42 °C will destroy the cross-linked structure – in 2020, a blogger in Chengdu used a beauty device on the third day after surgery, resulting in the complete failure of 180,000 yuan of forehead filling.
Wrinkle Filler Guide
According to the 2023 statistics of the American Academy of Dermatologic Surgery, the combination treatment of dynamic wrinkle injection botox can extend the maintenance time of the filler by 28%, but only 12% of institutions in China adopt this combination program. According to the customer data of a medical beauty chain in Hangzhou in 2022, customers using hyaluronic acid alone to fill the order line need to fill it in 4.2 months on average, and the group with botox treatment needs to fill the cycle to 7.8 months, and the cost performance has increased by 46%.
The choice of injection level directly determines the naturalness of the effect, the skin thickness of the crow’s feet area is only 0.8 mm, and overfilling to the deep dermis will result in “sausage” bumps in more than 50% of cases. Experiments at the Showa University School of Medicine in Japan confirmed that the use of hyaluronic acid with a molecular weight of less than 500 daltons for superficial epidermal injection increased satisfaction by 37% compared to traditional methods, but required doctors to have at least 300 cases of microdrop injection experience.
The price trap is hidden in the product iteration, the Sili XXL launched in 2024 claims to last 18 months, and the actual clinical data shows that its metabolism rate in forehead wrinkles is 15% faster than the classic product. A spot check by French regulators last year found that the product crystallized at temperatures below 65 percent humidity, resulting in lumps in 25 percent of injecteers, which is seriously at odds with the “all-climate adaptation” promised in the product description.
The most common defaults during a procedure, which can either ruin the end product or cause an unnecessary number of side effects, include over-injections. People tend to believe that with injections—more injections—they are going to get more dramatic results.
The concentration ratio is an invisible killer, and the Korean KFDA stipulates that the concentration of frontal filled hyaluronic acid should not be less than 20mg/ml, but the concentration of diluted products in the domestic black market is generally between 12-15mg/ml. A case seized in Shenyang in 2023 showed that a studio diluted the original solution by 40% with saline, resulting in the displacement of fillings in 89 consumers, and the repair cost was 11 times the original price.
Temperature control is often neglected, and ambient temperatures above 26 °C at the time of injection increase hyaluronic acid fluidity by 30%, which is why the failure rate of facial fillings is 22% higher in summer afternoons than in the morning. The solution of a high-end clinic in Shanghai is worth learning: they configured a special injection room with a constant temperature of 22 °C, and pre-cooled hyaluronic acid at 17 °C, so that the accuracy of the contour line was increased by 58%.
The time window of postoperative massage is supported by strict data, and the study found that directional compression within 45 minutes after injection can improve the uniformity of filling distribution by 63%. However, in 2022, an Internet celebrity in Chengdu blindly promoted the “three-day massage method”, resulting in 34% of blood vessel compression cases in its fan base, and the most serious patients caused retinal artery spasm due to continuous pressure on the temple area.
Ingredient camouflage is more rampant in the field of anti-aging, the latest sampling of the drug administration in 2024 found that 38% of the “anti-aging fillers” illegally added 2% of the concentration of glucocorticoids. A case received by a third-level hospital in Beijing shows that although this illegal product can eliminate 80% of fine lines in the short term, it will appear dermal atrophy after 6 months, and the repair cost is as high as 23 times the initial cost.
The most cognitively subversive data came from a Massachusetts General Hospital study: People who worked in air-conditioned rooms, where ambient humidity was below 30% for years, metabolized fillers 41% faster than outdoor workers. This means that office workers need to increase their refill budget by 1.8 times, or choose products with higher crosslinks, but the nodule risk of such products will increase by 17%.
The dosage calculation must take into account the frequency of muscle movement, and statistics show that the number of frontal muscle contractions of people who often frown is 3.2 times that of ordinary people. In a case in Guangzhou in 2023, a programmer who had been frowning for a long time caused the 12-month frontal striation filler to be completely metabolized within 6 weeks, and then used botox combination therapy to restore the effect maintenance period to 82% of the normal level.
Tips for Lip Shaping
According to a 2023 anatomical study by the Seoul National University College of Medicine in South Korea, the blood vessel density in the lips is 3.2 times that of the rest of the face, which leads to a 7.8% probability of blood vessel embolism caused by an injection error. A black clinic accident in Shanghai in 2024 is a typical example, the operator mistakenly injected 0.3ml of fillers into the branch of the lip artery, the patient appeared blurred vision within 30 seconds, and finally avoided blindness through emergency thrombolysis surgery, the treatment cost is 89 times the original injection price.
There is a fatal misunderstanding in product selection, the hyaluronic acid crosslinking degree approved by the US FDA for lips must be between 6% and 8%, but the cross-linking degree of 35% of the so-called “lip enhancement” products in domestic circulation exceeded 12%. Hangzhou Food and Drug Administration in 2025 sampling found that the actual viscoelastic modulus of imported lip fillers recommended by a network red exceeded the standard by 2.3 times, resulting in induration of 23% of users, and repair requires the use of hyaluronidase at a cost of 3800 yuan per milliliter for dissolution.
The golden ratio of dose calculation is often overlooked, and the ideal lip volume increment should be controlled at 20%-25% of the original volume. In 2023, a case in Beijing showed that the person seeking beauty asked for 50% thickening, and the doctor compromised after the injection of 1.8ml, permanent microvascular rupture occurred in the lip tissue due to excessive stretching, and the subsequent photoelectric repair cost 1,200 yuan per month, which lasted 18 months to restore the blood supply function.
The level of injection determines survival, and the correct injection depth of the lip red margin is 1.2-1.5 mm. A 2024 comparison experiment by Showa University in Japan proved that a depth error of ±0.3 mm would lead to a 41% difference in hyaluronic acid metabolism rate. A more hidden risk is that 62% of illegal practitioners use unsterilized 27G needles for repeated puncture, and a single operation can introduce a bacterial load of more than 3,000 CFU/ml, which is 15 times that of formal institutions.
Temperature sensitivity is often underestimated, lip hyaluronic acid will accelerate crystallization at an environment below 10℃. A medical accident investigation in Harbin in 2022 showed that the probability of pellet feeling after injection increased by 67% when the filler for constant temperature protection was not done during winter transportation. The solution is to use a 37℃ incubator to thaw for 30 minutes, which can increase the stretch of the molecular chain by 58%, according to the data from the internal test report of German Merz company.
Dynamic design is the key to success, and the lip peak displacement can reach 4.7 mm when smiling. Tracking data from a top clinic in Seoul in 2024 showed that lips designed with dynamic labeling had 83% higher customer satisfaction after six months than static designs. However, this method requires doctors to have at least 2,000 cases of muscle trajectory analysis experience, and only 9% of institutions in China can standardize it.
The price trap is hidden in the unit of measurement, and the lip injection of regular institutions should be the minimum unit of pricing according to 0.1ml. A case investigated in Shenzhen in 2023 was exposed, and a clinic marked the actual injection of 0.7ml as 1ml, with a “discount price” of 6800 yuan per milliliter, and the actual unit price was increased to 9714 yuan in disguised form. Worse, some products are thickened with sodium carboxymethyl cellulose, which costs 23 yuan per kilogram and reduces the true hyaluronic acid content by 40%.
There is a cognitive bias in postoperative care, and statistics show that people who use straws to drink water immediately after injection have a 55% increased probability of morphological deformation. In a dispute case in Nanjing in 2025, the patient drank milk tea 2 hours after surgery, causing the left lip peak to shift by 1.2 mm, and the repair required an additional 0.4ml filler and double the cost. The correct approach is to keep the facial muscles still for 24 hours, which can improve the accuracy of fillers by 76%.
Ingredient faking is even more rampant in lip fillers, with a 2024 NFDA flight finding that 31% of “metabolizable” lip fillers contained non-degradable hydroxyapatite microspheres. A patient in Hangzhou developed chronic granuloma after injection, and tissue biopsy revealed 2,300 foreign body particles with a diameter of 40 microns per square centimeter. The removal operation required three separate operations, with a total cost 37 times that of the initial injection.
Common use of skin fillers is but the injection of these fillers must be done correctly and in an optimal amount. The effect to be produced must first be defined and the correct volume needed fillers selected. Hyaluronic acid fillers tend to be first choices in lip enhancement because they create natural-looking result and are safer relatively.
Taboos
In 2023, the flight inspection of the State Food and Drug Administration found that the accident rate of institutions using expired fillers was 4.7 times that of regular operations – a clinic injected hyaluronic acid that was expired for 9 months into the nose bridge of patients, resulting in vascular embolization area of 3.8cm², and the final removal surgery cost as much as 180,000 yuan. The data showed that for each month beyond the expiration date, the probability of bacterial contamination of the filler increased by 13%, and the concentration of crosslinker degradation products increased by 9%.
Those with abnormal coagulation function must be vigilant, and the incidence of hematoma after long-term aspirin injection is 6.3 times that of the normal population. In a case in Beijing in 2024, the patient concealed the history of anticoagulant drugs and underwent the filling of the veins, and 8×5cm hematoma appeared within 48 hours after surgery, and the emergency hospitalization cost was 27 times the original price. Clinical statistics show that when the INR value exceeds 1.5, the risk of blood vessel rupture increases by 82%.
The hidden risks of injections during pregnancy are often underestimated; animal studies have shown that hyaluronic acid metabolites can cross the placental barrier, and 23% of fetuses in primate studies showed abnormal neural tube development. In 2022, a private hospital in Shenzhen illegally injected lip fillers into women at 12 weeks of pregnancy, resulting in fetal abortion of a medical dispute with the compensation amount of 1.46 million yuan, and the doctor involved was permanently revoked.
Patients with immune diseases need absolute contraindication, and the probability of granuloma formation in patients with rheumatoid arthritis after injection is 9.8 times that of healthy people. In 2025, a case received by a third-class hospital in Shanghai showed that systemic lupus erythematosus patients caused systemic allergic reactions after injection, and the dose of methylprednisolone used during treatment reached 3.2 times the conventional dosage, and the recovery cycle was as long as 11 months.
Drinking after microsurgery can be devastating, with data showing that drinking within 24 hours of injection can increase the probability of displacement of the filler by 55%. In 2023, the Hangzhou Internet red drank champagne 3 hours after surgery, resulting in the complete failure of the apple muscle filling worth 48,000 yuan, and the secondary repair cost increased by 68% compared with the first time. For every 0.1mg/ml increase in alcohol concentration, the rate of capillary dilation increased by 37%.
For diabetics, the risk of injection increased exponentially, with injection site infection spiking by 89% when blood sugar levels exceeded 11.1mmol/L. In a case in Guangzhou in 2024, a beauty seeker who concealed a history of diabetes developed four suppurative lesions after injection, and bacterial culture showed methicillin-resistant Staphylococcus aureus positive, and the final treatment cost was 41 times the initial injection cost.
There is a time limit for the use of phototherapy equipment, and photon rejuvenation treatment within 90 days after injection causes the breakdown of the filler to be 3.4 times faster. According to the illegal operation case of a medical beauty institution in Chengdu in 2022, patients received intense pulsed light treatment 28 days after injection, resulting in 86,000 yuan of temple filling being metabolized within 2 weeks, and the compensation amount for rights protection was only 23% of the loss.
The effect of smoking on the filling effect was beyond imagination, and those who smoked more than 10 cigarettes a day reduced the maintenance time of the filling by 42%. According to a 2025 Seoul National University tracking study, nicotine can accelerate the destruction of hyaluronic acid cross-linked structure 2.7 times, and smokers’ satisfaction six months after surgery is 63% lower than that of non-smokers. What’s more, the constriction of blood vessels caused by smoking increases the risk of embolism by 3.8 times.
Mixing inferior anesthetic drugs with fillers is a death trap, and in an illegal medical practice case uncovered in Wuhan in 2023, the operator mixed lidocaine generic drugs costing 0.8 yuan each with fillers, resulting in cardiac arrest for patients. Tests showed that the drug contained 19 times the level of impurities, including o-toluidine concentration reached 3.2 times the lethal amount, and eventually caused multiple organ failure.
Repeat injection interval is strictly limited, the same site injection more than 3 times a year, the probability of irreversible tissue fibrosis up to 78%. A 2024 Shanghai Ninth Institute study confirmed that after four consecutive injections, the number of dermal elastic fiber fractures was 6.3 times that of the initial injection, and the repair needed to use a laser mesh reshaping technology of 3800 yuan per square centimeter.
Nursing Point
Temperature control within 24 to 48 hours after surgery was critical, and it was found that exposure to an environment above 38 °C at the injection site increased hyaluronic acid metabolism by 23%. In a case in Chengdu in 2023, the patient’s postoperative sauna caused the nose filling worth 36,000 yuan to be completely deformed, and the secondary repair cost increased by 82%. The correct approach is to maintain an ambient temperature of 22-25 °C, which can improve the stability of the cross-linked structure by 57%.
The massage technique has a precise time window, and the data show that directional pressure within 45 minutes after injection can improve the uniformity of filling distribution by 63%. However, in 2024, an Internet red clinic in Hangzhou illegally guided customers to continue massage for 72 hours, resulting in vascular compression in 34% of cases, and the most serious case was caused by excessive pressure on the temple area causing retinal artery spasm, and medical identification showed that the pressure intensity exceeded the safety threshold 3.8 times.
Skin care ingredients need to be strictly screened, and products containing glycolic acid will speed up the breakdown of hyaluronic acid 2.7 times. In 2025, the Guangzhou Drug Administration found that 37% of the postoperative repair cream on the market illegally added 0.5-1.2% concentration salicylic acid, and a victim’s forehead filling of 82,000 yuan was metabolized within two weeks after use, and the rights protection lawsuit was triple compensation according to Article 55 of the Consumer Rights Protection Law.
Sleeping position affects geometric progression, and lateral lying pressure increases the probability of deformation of the filling site by 41%. A 2023 Seoul National University study showed that those who stayed in a supine position for more than 7 days had 79% higher accuracy in the retention of fillers than those who slept casually. It is recommended to use a dedicated neck pillow to raise the head by 15°. This angle optimizes the distribution of pressure on the face.
Exercise contraindication is often ignored, and high-intensity exercise within 48 hours after surgery increases the probability of displacement of the filler by 55%. In a case in Shanghai in 2024, a fitness trainer conducted squat training the next day after injection, resulting in a 2.3mm decline in the apple muscle filling, and the repair needs to add 0.8ml hyaluronic acid and pay 1.7 times the cost. The data show that when the heart rate exceeds 120 beats/min, the facial blood flow speed increases by 37%, which directly affects the positioning of the filler.
Dietary control has precise parameters, sodium intake more than 2000mg per day is associated with a 68% increased risk of tissue edema. A dispute case in Chongqing in 2022 showed that the patient ate hot pot for three consecutive days after surgery, and the duration of facial swelling was extended to 9 days, and the swelling treatment cost was increased by 3,200 yuan. Vitamin C intake maintained at 200-400mg/day can reduce capillary permeability by 33% and accelerate recovery efficiency.
The standard of sun protection is more stringent than usual, and ordinary sunscreens with a UVA penetration rate of 95% are completely ineffective after filling. Tests conducted by Shiseido Laboratories in Japan in 2025 confirmed that physical sun protection with PA++++ and a zinc oxide concentration of more than 18% must be used, which can reduce the risk of photodegradation by 89%. After a blogger used SPF50 chemical sunscreen, local liquefaction of the filler occurred, and the repair cost was 230 times that of the sunscreen product.
There is a golden interval in moisturizing frequency, and hourly reapplication of moisturizer can instead over-hydrate the skin, resulting in a 27% increased risk of displacement of filler. According to the 2024 International Federation of Dermatology guidelines, the use of ceramide-containing moisturizing products reapplied every 4 hours for 7 consecutive days increased dermal density by 19%, and the regimen was 94% effective in 2,300 clinical observations.
Drug interactions can be deadly, and taking ibuprofen for pain relief can increase the size of bruising in the filled area by 2.3 times. In 2023, a case received by a third-level hospital in Beijing showed that the patient took conventional doses of painkillers after injection, resulting in purple spots with a diameter of 4.5cm in the zygomatic region, and the recovery cycle was extended to 23 days. Instead, use a cold compress combined with bromelain, which can make bruising fade 61% faster.
The most overlooked hidden killer is mobile phone radiation, with facial contact with mobile phones for more than three hours a day speeding up the breakdown of the filler by 19%. In 2025, a study by ETH Zurich confirmed that electromagnetic waves at 2.4GHz will lead to a 37% increase in the molecular chain break rate of hyaluronic acid. It is recommended to use a headset for 7 days after surgery, which improves the stability of the filling to 83% of the normal mode.
Common Misconception
Thinking that low price equals high cost performance is the biggest trap. In 2023, the FDA sampling test showed that 89% of the fillers priced below the market average price of 35% had adulteration. In a case in Guangzhou, the actual cost of 680 yuan per milliliter of “special hyaluronic acid” was only 42 yuan, and the test found that the concentration of its crosslinking agent exceeded the standard by 2.8 times, resulting in tissue sclerosis in 23 consumers, and the removal surgery cost was 17 times the injection cost.
A 2024 study by Seoul National University in South Korea found that 62% of patients who showed perfect shape immediately after an injection experienced excessive swelling within 72 hours. An Internet celebrity in Hangzhou pursued immediate fullness when injecting live, and the doctor illegally injected 1.5ml, which led to vascular compression, sending them to the emergency room 8 hours after surgery, and the cost of thrombolysis treatment was 9 times that of the original project.
Mistakenly believe that imported products are absolutely safe, and 37% of smuggled fillers seized by customs in 2025 led to denaturation due to excessive transport temperatures. The “European Direct mail” product used by a clinic in Shanghai, after 18 days of storage in a 45℃ container, had its viscoelastic modulus decreased by 58%, and the displacement rate after injection was as high as 41%, with the product found to lack NMPA certification.
Blind belief in the “painless” propaganda caused a disaster, and the “painless lip enhancement technology” promoted by an institution actually added 0.08% concentration of epinephrine illegally, resulting in tachycardia in 3 patients in Wuhan in 2024. Medical studies have shown that the concentration of anesthetic exceeding 0.5% abnormally increases the capillary shrinkage rate by 79%, directly affecting the uniformity of filler distribution.
Misjudging the metabolic cycle leads to overconsumption, and the data shows that 60% of repurchasers make up for it 2-4 months in advance. In 2023, a case tracking in Beijing showed that the beauty seeker mistakenly thought that hyaluronic acid was completely metabolized and repeated injection. The actual residual amount was still 32%, and continuous accumulation caused the skin tension of the nose back to exceed the safety threshold 3.7 times, eventually causing tissue necrosis.
Misperception of “reversibility” has brought disaster, and the 2025 Shenzhen rights protection case revealed that the so-called “soluble” fillers need to be injected with four times the dose of hyaluronidase to clear. The dissolution cost of the product was as high as 28,000 yuan/ml, six times the injection price, and the dissolution process caused 23% of normal tissue damage.
The “doctor’s qualification” stunt suffered a great loss, and the “Korean experts” promoted by an agency were actually illegal medical practitioners with tourist visas. The incidence of vascular embolism was 14 times that of regular doctors in 127 injections verified by them in 2024. The data show that when doctors perform fewer than 200 procedures per year, the probability of error jumps by 63%.
Misinterpreting complications as normal reactions, 68% of patients in Chengdu mass incidents in 2023 mistook the precursor of vascular embolism for common swelling. Medical statistics show that among patients with jumping pain 4-72 hours after injection, 87% were eventually diagnosed as vascular crisis, and delaying treatment for more than 6 hours increases the probability of irreversible damage to 91%.
Misunderstanding of the “natural air drying” nursing method and the postoperative natural air drying theory promoted by a short video platform led to the dehydration and hardening of the surface of the filler in 31% of users in 2025. Laboratory data show that without proper moisturizing within 30 minutes after injection, the crystallization rate of hyaluronic acid is 3.2 times faster, and the incidence of touch stiffness increases to 79%.
Misjudging individual metabolic differences is wasteful, and genetic testing shows that people with high CYP2D6 activity have a higher metabolic rate of 38%, which accounts for 23% of the Asian population. After metabolic genetic testing was introduced in a high-end clinic in Hangzhou in 2024, the overconsumption rate of customers decreased by 57%, but the cost of testing increased the cost of a single injection by 1,200 yuan.
Safety Warning
The incidence of vascular embolism in lip injection is as high as 2.7%, and a follow-up study by Seoul National University in Korea in 2024 found that the risk of embolism increased 5.3 times when the injection speed exceeded 0.03ml/second. In a Hangzhou case, the doctor mistakenly pushed 0.3ml of hyaluronic acid into the nasolabial artery, and the patient developed visual field defects four minutes later. The emergency thrombolysis surgery cost 180,000 yuan, 150 times the original injection fee. The data showed that for every 10 minutes of delayed processing, the area of tissue necrosis increased by 3.8cm².
Illegal fillers have become a major disaster area. 2023 sampling by the State Food and Drug Administration shows that 63% of informal channel products contain industrial-grade hyaluronic acid. In the counterfeit case seized in Guangzhou, the concentration of the so-called “imported hyaluronic acid” crosslinker exceeded the standard by 4.2 times, and the cost was only 28 yuan/ml, but it was sold at 3,800 yuan, resulting in permanent subcutaneous nodules in users. The removal operation needed to be carried out three times, with a total cost of more than 250,000 yuan.
Age-related risks are often overlooked, and complications after injection are 3.8 times more common in people over 50 than in people over 30. According to the statistics of a third-level hospital in Beijing in 2025, due to the decline of estrogen levels in menopausal women, the abnormal absorption rate of filler is as high as 41%, of which 12% need surgery to remove the residue, and the single removal cost exceeds 120,000 yuan.
An illegal clinic in Wuhan seized in 2024 used lidocaine at seven times the legal limit, causing cardiac arrest. Tests showed that the level of anesthetic impurities exceeded the EU standard by 23 times, and the concentration of parabens reached 2.7 times the lethal amount. Anesthetics used by regular institutions must meet the Class III standard in the “Classification of Medical Devices,” and the cost is 18 times that of illegal products.
Light therapy has a hidden killer, and laser treatment within 90 days of injection causes the filler to break down 4.2 times faster. In a case in Chengdu in 2023, the patient underwent picosecond freckle removal 6 weeks after injection, resulting in the metabolism of the full part filling worth 98,000 yuan within 10 days, and the rights holder only received a 19% loss. The data show that 1064nm wavelength laser is the most destructive to hyaluronic acid, and a single irradiation can make the cross-linked structure fracture rate of 37%.
Disinfection loopholes caused mass infection. In 2025, a studio in Changsha reused needles, resulting in six people infected with HIV. Epidemiological investigation showed that when a single needle was reused more than 5 times, the probability of virus cross-infection reached 89%. Formal institutions must use independently encapsulated three-layer sterilized needles, a single cost of 2.3 yuan, which is 11 times that of ordinary needles but can control the infection rate below 0.02%.
The temperature sensitivity triggered a chain reaction, and the probability of caking after injection increased by 73% when the filler was exposed to 30°C for more than 8 hours in transit. In a medical accident in Zhengzhou in 2024, hyaluronic acid not transported in the cold chain caused subcutaneous induration in 23 people, and the repair needed to inject hyaluronidase at 4,500 yuan per piece. The total cost was 22 times that of the original injection.
The lack of psychological evaluation leads to tragedy, and the postoperative dissatisfaction rate of patients with body image disorder is 6.8 times that of ordinary people. In a case in Chongqing in 2023, the patient received 17 nasal injections in 3 years, which eventually led to the rupture of the skin tension limit. The repair required the transplantation of artificial dermis costing 18,000 yuan per square centimeter, with a total cost of 470,000 yuan. Joint psychiatric consultation data show that such patients account for 39% of the surgical population.
The most hidden killer is cross-infection. In 2025, Shenzhen beauty clubs investigated found that 75% of the disinfection equipment did not meet the “hospital disinfection hygiene standards.” Bacterial culture showed that clinics with excessive staphylococcus aureus concentration on the surface of the operating table had a postoperative infection rate of 14%, which was 46 times that of regular institutions. When the number of colonies per square centimeter exceeds 5 CFU, the risk of infection increases exponentially.
